Yes and no. Top Hat Attendance provides a 'geolocation' feature to prevent students from responding to attendance outside of a physical area. Top Hat questions do not have the geolocation feature so technically you cannot prevent students from responding to questions remotely. However, you can make it very difficult for students to respond correctly from a remote location.

Read the article How can I prevent students from responding to questions outside of the classroom with Top Hat? on oregonstate.teamdynamix.com

Note: geolocation is not applicable in the remote teaching environment.